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Computational drug discovery and repurposing for the treatment of COVID-19: A systematic review.


ABSTRACT:

Background

Since the beginning of the novel coronavirus (SARS-CoV-2) disease outbreak, there has been an increasing interest in finding a potential therapeutic agent for the disease. Considering the matter of time, the computational methods of drug repurposing offer the best chance of selecting one drug from a list of approved drugs for the life-threatening condition of COVID-19. The present systematic review aims to provide an overview of studies that have used computational methods for drug repurposing in COVID-19.

Methods

We undertook a systematic search in five databases and included original articles in English that applied computational methods for drug repurposing in COVID-19.

Results

Twenty-one original articles utilizing computational drug methods for COVID-1

SUBMITTER: Mohamed K 

PROVIDER: S-EPMC7676368 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature