Comparison of MR findings of acute traumatic peripheral nerve injury and acute compressive neuropathy in a rat model.

ABSTRACT:

Purpose

The treatment strategy is different for acute traumatic peripheral nerve injury and acute compressive neuropathy. This study aimed to compare magnetic resonance imaging (MRI) features of acute traumatic peripheral nerve injury and acute compressive neuropathy in a rat model.

Materials and methods

Twenty female Sprague-Dawley rats were divided into two groups. In the crush injury group (n = 10), the unilateral sciatic nerve was crushed using forceps to represent acute traumatic peripheral nerve injury. In the compression injury group (n = 10), the unilateral sciatic nerve was ligated using silk to represent acute compressive neuropathy. The MRI of eight rats from each group were acquired on postoperative days 3 and 10. Fat-suppressed T2-weighted images were acquired.

SUBMITTER: Kim BR 

PROVIDER: S-EPMC7676645 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature