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Spontaneous travelling cortical waves gate perception in behaving primates.

ABSTRACT: Perceptual sensitivity varies from moment to moment. One potential source of this variability is spontaneous fluctuations in cortical activity that can travel as waves¹. Spontaneous travelling waves have been reported during anaesthesia^2-7, but it is not known whether they have a role during waking perception. Here, using newly developed analytic techniques to characterize the moment-to-moment dynamics of noisy multielectrode data, we identify spontaneous waves of activity in the extrastriate visual cortex of awake, behaving marmosets (Callithrix jacchus). In monkeys trained to detect faint visual targets, the timing and position of spontaneous travelling waves before target onset predicted the magnitude of target-evoked activity and the likelihood of target detection. By contrast, spatially disorganized fluctuations of neural activity were much less predictive. These results reveal an important role for spontaneous travelling waves in sensory processing through the modulation of neural and perceptual sensitivity.

SUBMITTER: Davis ZW

PROVIDER: S-EPMC7677221 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Spontaneous travelling cortical waves gate perception in behaving primates.

Davis Zachary W ZW Muller Lyle L Martinez-Trujillo Julio J Sejnowski Terrence T Reynolds John H JH

Nature 20201007 7834

Perceptual sensitivity varies from moment to moment. One potential source of this variability is spontaneous fluctuations in cortical activity that can travel as waves<sup>1</sup>. Spontaneous travelling waves have been reported during anaesthesia<sup>2-7</sup>, but it is not known whether they have a role during waking perception. Here, using newly developed analytic techniques to characterize the moment-to-moment dynamics of noisy multielectrode data, we identify spontaneous waves of activity ...[more]

PMID: 33029013

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Dataset Information

Spontaneous travelling cortical waves gate perception in behaving primates.

Publications

Spontaneous travelling cortical waves gate perception in behaving primates.

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