Network-based approach highlighting interplay among anti-hypertensives: target coding-genes: diseases.

ABSTRACT: Elucidating the relation between the medicines: targets, targets: diseases and diseases: diseases are of fundamental significance as-is for societal benefit. Hypertension is one of the dangerous health conditions prevalent in society, is a risk factor for several other diseases if left untreated and anti-hypertensives (AHs) are the approved drugs to treat it. The goal of the study is to decipher the connection between hypertension with other health conditions, however, is challenging due to the large interactome. To fulfill the aim, the strategy involves prior clustering of the AHs into groups as per our previous method, followed by the analyzing functional association of the target coding-genes (tc-genes) and health conditions for each group. Following our recently published work where th

SUBMITTER: Sharma R 

PROVIDER: S-EPMC7677320 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature