Rheumatic involvement and bone scan features in Schnitzler syndrome: initial and follow-up data from a single-center cohort of 25 patients.

ABSTRACT:

Objective

To report on the characteristics and long-term course of rheumatic manifestations in Schnitzler syndrome (SchS).

Methods

A retrospective cohort study of patients with SchS followed between 2000 and 2020. Inclusion criteria included a diagnosis of SchS (Strasbourg criteria). All available bone scans were reviewed and scored according to the intensity and number of pathological sites. The scintigraphic score was compared with the clinical activity score, CRP level, and treatments.

Results

Twenty-five patients were included. Median age at diagnosis was 68 years. Eighty patients (72%) had SchS-related rheumatic pain. Most patients had a long-standing isolated rash before constitutional and/or rheumatic symptoms appeared. The monoclonal component level was usuall

SUBMITTER: Darrieutort-Laffite C 

PROVIDER: S-EPMC7677784 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature