Antimicrobial use and production system shape the fecal, environmental, and slurry resistomes of pig farms.

ABSTRACT:

Background

The global threat of antimicrobial resistance (AMR) is a One Health problem impacted by antimicrobial use (AMU) for human and livestock applications. Extensive Iberian swine production is based on a more sustainable and eco-friendly management system, providing an excellent opportunity to evaluate how sustained differences in AMU impact the resistome, not only in the animals but also on the farm environment. Here, we evaluate the resistome footprint of an extensive pig farming system, maintained for decades, as compared to that of industrialized intensive pig farming by analyzing 105 fecal, environmental and slurry metagenomes from 38 farms.

Results

Our results evidence a significantly higher abundance of antimicrobial resistance genes (ARGs) on intensive farms an

SUBMITTER: Mencia-Ares O 

PROVIDER: S-EPMC7678069 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature