Does prophylactic antibiotic administration for tooth extraction affect PT-INR in patients taking warfarin?

ABSTRACT:

Background

Various antibiotics and analgesics have been reported to interact with warfarin. Reports that investigate the effects of medication taken for just a few days during tooth extraction on the prothrombin time-international normalized ratio are rare.

Methods

A total of 110 patients receiving long-term stable warfarin therapy underwent tooth extraction without interruption of warfarin treatment. INR values were measured 1 month before the tooth extraction, the day of the extraction, and 1 week after the extraction. We investigated the changes in INR values between the day of extraction and 1 week after extraction, as well as the various risk factors for increases in INR values.

Results

Before and after tooth extraction, the number of patients taking cefcapene pi

SUBMITTER: Iwata E 

PROVIDER: S-EPMC7678308 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature