Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study.

ABSTRACT:

Objectives

We aimed to investigate demographic, lifestyle, socioeconomic and clinical risk factors for COVID-19, and compared them to risk factors for pneumonia and influenza in UK Biobank.

Design

Cohort study.

Setting

UK Biobank.

Participants

49-83 year olds (in 2020) from a general population study.

Main outcome measures

Confirmed COVID-19 infection (positive SARS-CoV-2 test). Incident influenza and pneumonia were obtained from primary care data. Poisson regression was used to study the association of exposure variables with outcomes.

Results

Among 235 928 participants, 397 had confirmed COVID-19. After multivariable adjustment, modifiable risk factors were higher body mass index and higher glycated haemoglobin (HbA1C) (RR 1.28 and RR 1.14 per S

SUBMITTER: Ho FK 

PROVIDER: S-EPMC7678347 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature