Repeat screening for syphilis in pregnancy as an alternative screening strategy in the UK: a cost-effectiveness analysis.

ABSTRACT:

Objectives

To assess the cost-effectiveness of universal repeat screening for syphilis in late pregnancy, compared with the current strategy of single screening in early pregnancy with repeat screening offered only to high-risk women.

Design

A decision tree model was developed to assess the incremental costs and health benefits of the two screening strategies. The base case analysis considered short-term costs during the pregnancy and the initial weeks after delivery. Deterministic and probabilistic sensitivity analyses and scenario analyses were conducted to assess the robustness of the results.

Setting

UK antenatal screening programme.

Population

Hypothetical cohort of pregnant women who access antenatal care and receive a syphilis screen in 1 year.

Primar

SUBMITTER: Huntington S 

PROVIDER: S-EPMC7678359 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature