Main bronchus location is a predictor for metastasis and prognosis in lung adenocarcinoma: A large cohort analysis.

ABSTRACT:

Objectives

In the literature, inconsistent associations between the primary locations of lung adenocarcinomas (ADCs) with patient prognosis have been reported, due to varying definitions for central and peripheral locations. In this study, we investigated the clinical characteristics and prognoses of ADCs located in the main bronchus.

Methods

A total of 397,189 lung ADCs registered from 2004 to 2013 in the National Cancer Database (NCDB) were extracted and divided into main bronchus-located ADCs (2.5%, N = 10,111) and non-main bronchus ADCs (97.5%, N = 387,078). The ADCs located in the main bronchus and those not in the main bronchus were compared in terms of patient prognosis, lymph node involvement, distant metastases and other clinical features, including rate of curative

SUBMITTER: Yang L 

PROVIDER: S-EPMC7678407 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature