A new fat-dissociation method to detect lymph nodes in colorectal cancer: a prospective randomized study.

ABSTRACT: Histological examination of the lymph nodes (LNs) is crucial to determine the colorectal cancer (CRC) stage. We previously reported a new fat-dissociation method (FM) to detect LNs from surgically resected mesentery. This study aimed to examine the effectiveness of FM compared with that of conventional palpation method (PM) in CRC. This single-center, open-label, randomized controlled study was performed at Osaka International Cancer Institute in Japan in 2014. Randomization was performed using a computer-generated permuted-block sequence. Patients were stratified by surgical procedures and the LN dissection area. The primary endpoint was the time required for LN identification. The secondary endpoint was the number of LNs and 5-year cancer-specific survival. The 130 enrolled patients were

SUBMITTER: Fujino S 

PROVIDER: S-EPMC7678840 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature