The applicability of non-invasive methods for assessing liver fibrosis in hemodialysis patients with chronic hepatitis C.

ABSTRACT:

Background

The accurate assessment of liver fibrosis among hemodialysis patients with chronic hepatitis C (CHC) is important for both treatment and for follow up strategies. Applying the non-invasive methods in general population with viral hepatitis have been successful but the applicability of the aminotransferase/platelet ratio index (APRI) or the fibrosis-4 index (FIB-4) in hemodialysis patients need further evaluation.

Materials and methods

We conducted a prospective, multi-center, uremic cohort to verify the applicability of APRI and FIB-4 in identifying liver fibrosis by reference with the standard transient elastography (TE) measures.

Results

There were 116 CHC cases with valid TE were enrolled in our analysis. 46 cases (39.6%) were classified as F1, 35 cases

SUBMITTER: Lee JJ 

PROVIDER: S-EPMC7678992 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature