Autochthonous faecal viral transfer (FVT) impacts the murine microbiome after antibiotic perturbation.

ABSTRACT:

Background

It has become increasingly accepted that establishing and maintaining a complex and diverse gut microbiota is fundamental to human health. There are growing efforts to identify means of modulating and influencing the microbiota, especially in individuals who have experienced a disruption in their native microbiota. Faecal microbiota transplantation (FMT) is one method that restores diversity to the microbiota of an individual by introducing microbes from a healthy donor. FMT introduces the total microbial load into the recipient, including the bacteria, archaea, yeasts, protists and viruses. In this study, we investigated whether an autochthonous faecal viral transfer (FVT), in the form of a sterile faecal filtrate, could impact the recovery of a bacteriome disrupted by

SUBMITTER: Draper LA 

PROVIDER: S-EPMC7679995 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature