A blinded, controlled trial of objective measurement in Parkinson's disease.

ABSTRACT: Medical conditions with effective therapies are usually managed with objective measurement and therapeutic targets. Parkinson's disease has effective therapies, but continuous objective measurement has only recently become available. This blinded, controlled study examined whether management of Parkinson's disease was improved when clinical assessment and therapeutic decisions were aided by objective measurement. The primary endpoint was improvement in the Movement Disorder Society-United Parkinson's Disease Rating Scale's (MDS-UPDRS) Total Score. In one arm, objective measurement assisted doctors to alter therapy over successive visits until objective measurement scores were in target. Patients in the other arm were conventionally assessed and therapies were changed until judged optimal.

SUBMITTER: Woodrow H 

PROVIDER: S-EPMC7680151 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature