Indoor endotoxin, proximity to a major roadway, and severe asthma exacerbations among children in Puerto Rico.

ABSTRACT:

Background

Few studies have examined concurrent exposure to household endotoxin and traffic-related air pollution in relation to childhood asthma, yet both factors are associated with asthma outcomes.

Objective

To examine whether proximity to a major roadway (a traffic-related air pollution proxy) modifies the estimated effects of indoor endotoxin on asthma outcomes in children.

Methods

Cross-sectional study of 200 children with asthma (ages, 6-14 years) living in Puerto Rico. Residential distance to a major roadway was calculated as the distance from the participant's residential US census block centroid to the nearest major road. The outcomes of interest were severe asthma exacerbations, missed school days for asthma, atopy, lung function, and bronchodilator respons

SUBMITTER: Rosser F 

PROVIDER: S-EPMC7680389 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature