C-reactive protein concentration as a risk predictor of mortality in intensive care unit: a multicenter, prospective, observational study.

ABSTRACT:

Background

It is not clear whether there are valuable inflammatory markers for prognosis judgment in the intensive care unit (ICU). We therefore conducted a multicenter, prospective, observational study to evaluate the prognostic role of inflammatory markers.

Methods

The clinical and laboratory data of patients at admission, including C-reactive protein (CRP), were collected in four general ICUs from September 1, 2018, to August 1, 2019. Multivariate logistic regression was used to identify factors independently associated with nonsurvival. The area under the receiver operating characteristic curve (AUC-ROC), net reclassification improvement (NRI), and integrated discrimination improvement (IDI) were used to evaluate the effect size of different factors in predicting mortali

SUBMITTER: Qu R 

PROVIDER: S-EPMC7680994 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature