Lethal COVID-19: Radiologic-Pathologic Correlation of the Lungs.

ABSTRACT:

Purpose

The purpose of this retrospective study was to correlate CT patterns of fatal cases of coronavirus disease 2019 (COVID-19) with postmortem pathology observations.

Materials and methods

The study included 70 lung lobes of 14 patients who died of reverse-transcription polymerase chain reaction-confirmed COVID-19. All patients underwent antemortem CT and autopsy between March 9 and April 30, 2020. Board-certified radiologists and pathologists performed lobewise correlations of pulmonary observations. In a consensus reading, 267 radiologic and 257 histopathologic observations of the lungs were recorded and systematically graded according to severity. These observations were matched and evaluated.

Results

Predominant CT observations were ground-glass opacities (GGO

SUBMITTER: Henkel M 

PROVIDER: S-EPMC7681778 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature