Chicken cecal DNA methylome alteration in the response to Salmonella enterica serovar Enteritidis inoculation.

ABSTRACT:

Background

Salmonella enterica serovar Enteritidis (SE) is one of the pathogenic bacteria, which affects poultry production and poses a severe threat to public health. Chicken meat and eggs are the main sources of human salmonellosis. DNA methylation is involved in regulatory processes including gene expression, chromatin structure and genomic imprinting. To understand the methylation regulation in the response to SE inoculation in chicken, the genome-wide DNA methylation profile following SE inoculation was analyzed through whole-genome bisulfite sequencing in the current study.

Results

There were 185,362,463 clean reads and 126,098,724 unique reads in the control group, and 180,530,750 clean reads and 126,782,896 unique reads in the inoculated group. The methylation densit

SUBMITTER: Wang Y 

PROVIDER: S-EPMC7681971 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature