Investigational and Experimental Drugs for Community-Acquired Pneumonia: the Current Evidence.

ABSTRACT: Community-acquired pneumonia (CAP) is a common infection with a constantly evolving etiological spectrum. This changing etiology conditions the adequate selection of optimal therapeutic regimens, both in empirical and definitive treatments. In recent years, new antimicrobials have been approved by regulatory authorities for use in CAP, although it is necessary to continue incorporating new antimicrobial agents that improve the activity profile in relation to the appearance of bacterial resistance in certain pathogens, such as pneumococcus, Staphylococcus aureus or Pseudomonas aeruginosa. Delafloxacin, omadacycline and lefamulin are the most recently approved antibiotics for CAP. These three antibiotics have shown non-inferiority to their comparators for the treatment of CAP w

SUBMITTER: Sellares-Nadal J 

PROVIDER: S-EPMC7682597 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature