Orthostatic hypotension, dizziness, neurology outcomes, and death in older adults.

ABSTRACT:

Objective

To test the hypothesis that orthostatic hypotension (OH) might cause cerebral hypoperfusion and injury, we examined the longitudinal relationship between OH or orthostatic symptoms and incident neurologic outcomes in a community population of older adults.

Methods

Cardiovascular Health Study participants (≥65 years) without dementia or stroke had blood pressure (BP) measured after lying down for 20 minutes and after standing 3 for minutes. Participants reported dizziness immediately upon standing and any dizziness in the past 2 weeks. OH was defined as a drop in standing systolic/diastolic BP ≥20/≥10 mm Hg. We determined the association between OH or dizziness with (1) MRI brain findings (ventricular size, white matter hyperintensities, brain infarcts) using linear

SUBMITTER: Juraschek SP 

PROVIDER: S-EPMC7682840 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature