Absence-to-bilateral-tonic-clonic seizure: A generalized seizure type.

ABSTRACT:

Objective

To test the hypothesis that absence seizures can evolve to generalized tonic-clonic seizures, we documented electroclinical features of this novel seizure type.

Methods

In 4 large video-EEG databases, we identified recordings of seizures starting with impaired awareness that, without returning to baseline interictal state, evolved to generalized tonic-clonic seizures. We extracted the detailed semiologic and electrographic characteristics of these seizures, and we documented the clinical background, diagnoses, and therapeutic responses in these patients.

Results

We identified 12 seizures from 12 patients. All seizures started with a period of impaired awareness and bursts of generalized spike or polyspike and slow-wave discharges, the hallmark of absence sei

SUBMITTER: Beniczky S 

PROVIDER: S-EPMC7682845 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature