Investigating the human protein-host protein interactome of SARS-CoV-2 infection in the small intestine.

ABSTRACT:

Aim

The present study aimed to identify human protein-host protein interactions of SARS-CoV-2 infection in the small intestine to discern the potential mechanisms and gain insights into the associated biomarkers and treatment strategies.

Background

Deciphering the tissue and organ interactions of the SARS-CoV-2 infection can be important to discern the potential underlying mechanisms. In the present study, we investigated the human protein-host protein interactions in the small intestine.

Methods

Public databases and published works were used to collect data related to small intestine tissue and SARS-CoV-2 infection. We constructed a human protein-protein interaction (PPI) network and showed interactions of host proteins in the small intestine. Associated modules, bio

SUBMITTER: Khodadoost M 

PROVIDER: S-EPMC7682973 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature