Intratumoral and peritumoral radiomics analysis for preoperative Lauren classification in gastric cancer.

ABSTRACT:

Background

Preoperative prediction of the Lauren classification in gastric cancer (GC) is very important to the choice of therapy, the evaluation of prognosis, and the improvement of quality of life. However, there is not yet radiomics analysis concerning the prediction of Lauren classification straightly. In this study, a radiomic nomogram was developed to preoperatively differentiate Lauren diffuse type from intestinal type in GC.

Methods

A total of 539 GC patients were enrolled in this study and later randomly allocated to two cohorts at a 7:3 ratio for training and validation. Two sets of radiomic features were derived from tumor regions and peritumor regions on venous phase computed tomography (CT) images, respectively. With the least absolute shrinkage and selection op

SUBMITTER: Wang XX 

PROVIDER: S-EPMC7684959 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature