Dose point kernels for 2,174 radionuclides.

ABSTRACT:

Purpose

Rapid adoption of targeted radionuclide therapy as an oncologic intervention has motivated the development of patient-specific voxel-wise approaches to radiation dosimetry. These approaches often rely on pretabulated dose point kernels for convolution-based calculations; however, these dose kernels are sparse in literature and often have suboptimal characteristics. The purpose of this work was to generate an extensive library of dose point kernels with sufficient size and resolution for general clinical application of voxel-wise dosimetry.

Methods

Nuclear data were acquired for 2174 radionuclides from the National Nuclear Data Center (Brookhaven National Laboratory, accessed March 2018). Based on these data, isotropic point sources of radioactivity in water were simu

SUBMITTER: Graves SA 

PROVIDER: S-EPMC7685392 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature