The Role of Topical Antibiotic Prophylaxis in Oculofacial Plastic Surgery: A Randomized Controlled Study.

ABSTRACT:

Purpose

The usefulness of topical antibiotic prophylaxis for routine oculofacial plastic surgery is not well established. Given concerns such as contact dermatitis, antibiotic resistance, and healthcare costs in conjunction with a low baseline rate of surgical site infections, the investigators sought to determine the frequency of infection with and without the use of topical antibiotic prophylaxis.

Design

Randomized, controlled, unmasked clinical trial.

Participants

Adult patients undergoing routine periocular surgery without prior history of periocular surgical site infection, need for perioperative oral or parenteral antibiotics, or allergy to all study medications.

Methods

Participants were randomized before surgery to receive either antibiotic or placebo (

SUBMITTER: Ashraf DC 

PROVIDER: S-EPMC7686086 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature