Collagen denaturation is initiated upon tissue yield in both positional and energy-storing tendons.

ABSTRACT: Tendons are collagenous soft tissues that transmit loads between muscles and bones. Depending on their anatomical function, tendons are classified as positional or energy-storing with differing biomechanical and biochemical properties. We recently demonstrated that during monotonic stretch of positional tendons, permanent denatured collagen begins accumulating upon departing the linear region of the stress-strain curve. However, it is unknown if this observation is true during mechanical overload of other types of tendons. Therefore, the purpose of this study was to investigate the onset of collagen denaturation relative to applied strain, and whether it differs between the two tendon types. Rat tail tendon (RTT) fascicles and rat flexor digitorum longus (FDL) tendons represented positiona

SUBMITTER: Lin AH 

PROVIDER: S-EPMC7686113 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature