Diabetic Retinopathy and Risk of Stroke: A Secondary Analysis of the ACCORD Eye Study.

ABSTRACT:

Background and purpose

Diabetic retinopathy (DR) is a common microvascular complication of diabetes, which causes damage to the retina and may lead to rapid vision loss. Previous research has shown that the macrovascular complications of diabetes, including stroke, are often comorbid with DR. We sought to explore the association between DR and subsequent stroke events.

Methods

This is a secondary analysis of patients enrolled in the ACCORD Eye study (Action to Control Cardiovascular Risk in Diabetes). The primary outcome was stroke during follow-up. The exposure was presence of DR at study baseline. We fit adjusted Cox proportional hazards models to provide hazard ratios for stroke and included interaction terms with the ACCORD randomization arms.

Results

We included

SUBMITTER: Wong KH 

PROVIDER: S-EPMC7686117 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature