A simulated model for fluid and tissue heating during pediatric laser lithotripsy.

ABSTRACT:

Background

Laser lithotripsy (LL) is a common modality for treatment of children and adolescents with nephrolithiasis. Recent introduction of higher-powered lasers may result in more efficacious "dusting" of urinary calculi. However, in vivo animal studies and computational simulations have demonstrated rapid and sustained rise of fluid temperatures with LL, possibly resulting in irreversible tissue damage. How fluid and tissue heating during LL vary with pediatric urinary tract development, however, is unknown. We hypothesize that kidneys of younger children will be more susceptible to changes in fluid temperature and therefore tissue damage than those of older children.

Methods

Computational simulations were developed for LL in children utilizing COMSOL Multiphysics finite

SUBMITTER: Ellison JS 

PROVIDER: S-EPMC7686138 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature