Prospective evaluation of multitarget treatment of pediatric patients with helical intensity-modulated radiotherapy.

ABSTRACT:

Background and purpose

Radiotherapy (RT) is persistently gaining significance in the treatment of pediatric tumors. However, individual features of a growing body and multifocal stages complicate this approach. Tomotherapy offers advantages in the treatment of anatomically complex tumors with low risks of side effects. Here we report on toxicity incidence and outcome of tomotherapy with a focus on multitarget RT (mtRT).

Materials and methods

From 2008 to 2017, 38 children diagnosed with sarcoma were treated with tomotherapy. The median age was 15 years (6-19 years). Toxicity was graded according to the Common Terminology Criteria for Adverse Events v.4.03 and classified into symptoms during RT, acutely (0-6 months) and late (>6 months) after RT, and long-term sideeffects (>2

SUBMITTER: Salfelder MA 

PROVIDER: S-EPMC7686189 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature