Efficacy and tolerability of nortriptyline in the management of neuropathic corneal pain.

ABSTRACT:

Purpose

Neuropathic corneal pain (NCP) is a recently acknowledged disease entity. However, there is no consensus in potential treatment strategies, particularly in patients with a centralized component of pain. This study aims to assess the efficacy and tolerability of the tricyclic antidepressant, nortriptyline, among NCP patients.

Methods

Patients with clinically diagnosed NCP and a centralized component of pain, treated with oral nortriptyline, who had recorded pain scores as assessed by the ocular pain assessment survey at the first and last visit were included. Patients were excluded if they had any other ocular pathology that might result in pain or had less than 4 weeks of nortriptyline use. Demographics, time between visits, concomitant medications, systemic and ocul

SUBMITTER: Ozmen MC 

PROVIDER: S-EPMC7686298 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature