The effect of gadolinium-based contrast agent administration on magnetic resonance fingerprinting-based T₁ relaxometry in patients with prostate cancer.

ABSTRACT: Magnetic resonance fingerprinting (MRF) is a rapidly developing fast quantitative mapping technique able to produce multiple property maps with reduced sensitivity to motion. MRF has shown promise in improving the diagnosis of clinically significant prostate cancer but requires further validation as part of a prostate multiparametric (mp) MRI protocol. mpMRI protocol mandates the inclusion of dynamic contrast enhanced (DCE) imaging, known for its significant T₁ shortening effect. MRF could be used to measure both pre- and post-contrast T₁ values, but its utility must be assessed. In this proof-of-concept study, we sought to evaluate the variation in MRF T₁ measurements post gadolinium-based contrast agent (GBCA) injection and the utility of such T₁

SUBMITTER: Sushentsev N 

PROVIDER: S-EPMC7686305 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature