Occult Talaromyces marneffei Infection Unveiled by the Novel Mp1p Antigen Detection Assay.

ABSTRACT: Talaromyces marneffei causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture-negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation.

SUBMITTER: Ly VT 

PROVIDER: S-EPMC7686654 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature