Tailored immunosuppression after kidney transplantation - a single center real-life experience.

ABSTRACT:

Background

Kidney allograft survival continuously improved with introduction of novel immunosuppressants. However, also immunologically challenging transplants (blood group incompatibility and sensitized recipients) increase. Between 2006 and 2008, a new tailored immunosuppression scheme for kidney transplantation was implemented at the University Hospital in Zurich, together with an ABO-incompatible transplant program and systematic pre- and posttransplant anti-human leukocyte antigen (HLA) antibody screening by Luminex technology. This study retrospectively evaluated the results of this tailored immunosuppression approach with a particular focus on immunologically higher risk transplants.

Methods

A total of 204 consecutive kidney transplantations were analyzed, of whom 14

SUBMITTER: Good-Weber M 

PROVIDER: S-EPMC7686677 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature