Reliability and validity of the Vitiligo Signs of Activity Score (VSAS).

ABSTRACT:

Background

The associations between disease activity and several clinical signs in vitiligo have been described, but a widely accepted and validated scoring system is lacking.

Objectives

To validate the Vitiligo Signs of Activity Score (VSAS) for physicians.

Methods

Three visible clinical signs were scored on 15 body locations: confetti-like depigmentation (c), Koebner phenomenon (k) and hypochromic areas/borders (h). The inter- and intrarater reliability of the global VSAS and VSAS subscores (c-VSAS, k-VSAS and h-VSAS) were tested by four and three raters (physicians), respectively. Construct validity and feasibility were evaluated.

Results

The VSAS demonstrated good inter-rater reliability, with an intraclass correlation coefficient (ICC) of 0·87 in the first

SUBMITTER: van Geel N 

PROVIDER: S-EPMC7687072 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature