Application of a Mapping Function to Estimate Utilities for Ragweed Allergy Immunotherapy Trials.

ABSTRACT: BACKGROUND:Ragweed pollen sensitivity is a common cause of allergic rhinitis (AR) worldwide. AR symptoms include itchy and runny eyes, sneezing, blocked nose, impaired sleep and social and emotional problems, which can have a significant impact on quality of life. OBJECTIVE:The objective of this analysis was to estimate utilities for two pooled standardised quality (SQ) ragweed sublingual immunotherapy (SLIT) tablet trials by applying a previously developed mapping algorithm. This study validated the algorithm and extended its application to ragweed seasonal allergy trials. The mapping algorithm relates disease-specific quality-of-life scores to preference-based utilities that may be used to calculate quality-adjusted life-years (QALYs) in cost-effectiveness studies. METHODS:A mapping algo

SUBMITTER: Dick K 

PROVIDER: S-EPMC7688878 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature