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Effects of norfluoxetine and venlafaxine in zebrafish larvae: Molecular data.


ABSTRACT: The data presented herein relates to the article entitled "Norfluoxetine and venlafaxine in zebrafish larvae: single and combined toxicity of two pharmaceutical products relevant for risk assessment" [1]. Recent studies have shown the occurrence of active metabolites of human and veterinary pharmaceuticals in surface and wastewaters. Besides their biological activity, some are predicted to interact with the same molecular targets of their parental compounds, thus showing the potential to elicit detrimental effects on animals. Despite this, limited investigation on their effects on aquatic animals has been done. Genomic material resulting from zebrafish (Danio rerio) larvae exposed to the psychoactive compounds norfluoxetine (main fluoxetine metabolite), venlafaxine, or their mixture

SUBMITTER: Rodrigues P 

PROVIDER: S-EPMC7689041 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature