Prenatal stress exposure and multimodal assessment of amygdala-medial prefrontal cortex connectivity in infants.

ABSTRACT: Stressful experiences are linked to neurodevelopment. There is growing interest in the role of stress in the connectivity between the amygdala and medial prefrontal cortex (mPFC), a circuit that subserves automatic emotion regulation. However, the specific timing and mechanisms that underlie the association between stress and amygdala-mPFC connectivity are unclear. Many factors, including variations in fetal exposure to maternal stress, appear to affect early developing brain circuitry. However, few studies have examined the associations of stress and amygdala-mPFC connectivity in early life, when the brain is most plastic and sensitive to environmental influence. In this longitudinal pilot study, we characterized the association between prenatal stress and amygdala-mPFC connectivity in yo

SUBMITTER: Humphreys KL 

PROVIDER: S-EPMC7689043 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature