Ketamine for the treatment of prehospital acute pain: a systematic review of benefit and harm.

ABSTRACT:

Background

Few publications have addressed prehospital use of ketamine in analgesic doses. We aimed to assess the effect and safety profile of ketamine compared with other analgesic drugs (or no drug) in adult prehospital patients with acute pain.

Methods

A systematic review of clinical trials assessing prehospital administration of ketamine in analgesic doses compared with other analgesic drugs or no analgesic treatment in adults. We searched PubMed, EMBASE, Cochrane Library and Epistemonikos from inception until 15 February 2020, including relevant articles in English and Nordic languages. We used the Cochrane and Grading of Recommendations Assessment, Development and Evaluation methodologies and exclusively assessed patient-centred outcomes. Two independent authors screen

SUBMITTER: Sandberg M 

PROVIDER: S-EPMC7689093 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature