Parity predicts biological age acceleration in post-menopausal, but not pre-menopausal, women.

ABSTRACT: Understanding factors contributing to variation in 'biological age' is essential to understanding variation in susceptibility to disease and functional decline. One factor that could accelerate biological aging in women is reproduction. Pregnancy is characterized by extensive, energetically-costly changes across numerous physiological systems. These 'costs of reproduction' may accumulate with each pregnancy, accelerating biological aging. Despite evidence for costs of reproduction using molecular and demographic measures, it is unknown whether parity is linked to commonly-used clinical measures of biological aging. We use data collected between 1999 and 2010 from the National Health and Nutrition Examination Survey (n = 4418) to test whether parity (number of live births) predicted four pr

SUBMITTER: Shirazi TN 

PROVIDER: S-EPMC7689483 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature