Genomic islands and the evolution of livestock-associated Staphylococcus aureus genomes.

ABSTRACT: Genomic Islands (GIs) are commonly believed to be relics of horizontal transfer and associated with specific metabolic capacities, including virulence of the strain. Horizontal gene transfer (HGT) plays a vital role in the acquisition of GIs and the evolution and adaptation of bacterial genomes. The present study was designed to predict the GIs and role of HGT in evolution of livestock-associated Staphylococcus aureus (LA-SA). GIs were predicted with two methods namely, Ensemble algorithm for Genomic Island Detection (EGID) tool, and Seq word Sniffer script. Functional characterization of GI elements was performed with clustering of orthologs. The putative donor predictions of GIs was done with the aid of the pre_GI database. The present study predicted a pan of 46 GIs across the LA-SA gen

SUBMITTER: Rao RT 

PROVIDER: S-EPMC7689654 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature