Effect of understaging on local recurrence of rectal cancer.

ABSTRACT:

Background and objectives

Magnetic resonance imaging of the pelvis has a limited accuracy to detect positive lymph nodes but does dictate neoadjuvant treatment in rectal cancer. This study aimed to investigate preoperative lymph node understaging and its effects on postoperative local recurrence rate.

Methods

Patients were selected from a retrospective cross-sectional snapshot study. Patients with emergency surgery, cM1 disease, or unknown cN- or (y)pN category were excluded. Clinical and pathologic N-categories were compared and the impact on local recurrence was determined by multivariable analysis.

Results

Out of 1548 included patients, 233 had preoperatively underestimated lymph node staging based on (y)pN category. Out of the 695 patients staged cN0, 168 (24%) ha

SUBMITTER: Giesen LJX 

PROVIDER: S-EPMC7689834 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature