CAPRIB: a user-friendly tool to study amino acid changes and selection for the exploration of intra-genus evolution.

ABSTRACT:

Background

The evolution of bacteria is shaped by different mechanisms such as mutation, gene deletion, duplication, or insertion of foreign DNA among others. These genetic changes can accumulate in the descendants as a result of natural selection. Using phylogeny and genome comparisons, evolutionary paths can be somehow retraced, with recent events being much easier to detect than older ones. For this reason, multiple tools are available to study the evolutionary events within genomes of single species, such as gene composition alterations, or subtler mutations such as SNPs. However, these tools are generally designed to compare similar genomes and require advanced skills in bioinformatics. We present CAPRIB, a unique tool developed in Java that allows to determine the amino acid

SUBMITTER: Guerra Maldonado JF 

PROVIDER: S-EPMC7690079 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature