Effect of e-cigarette flavors on nicotine delivery and puffing topography: results from a randomized clinical trial of daily smokers.

ABSTRACT:

Rationale

There is limited understanding regarding how various e-cigarette flavorings may influence the behavior of non-regular e-cigarette users who are regular cigarette smokers.

Objectives

To assess differences in nicotine delivery, puffing topography, subjective effects, and user satisfaction from different flavored e-liquids.

Methods

Eighteen daily smokers (average age, 44.1 ± 7.0; 9 males; average CPD, 13.0 ± 5.8) smoked their tobacco cigarettes during an initial visit and returned five times to try an e-cigarette (eGo type) refilled with a nicotine solution (24 mg/ml) of five different flavors: cherry, tobacco, espresso, menthol, and vanilla (randomized order). Assessments at each visit included puffing topography, blood samples for nicotine analysis, and subje

SUBMITTER: Voos N 

PROVIDER: S-EPMC7691130 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature