Prenatal vitamin D supplementation and child respiratory health: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Systematic review and meta-analyses of observational studies on maternal vitamin D status and risk of respiratory allergic conditions indicated that mothers who had supplementation during pregnancy could decrease the risk of recurrent wheeze or asthma in their offspring.

Objectives

We conducted this meta-analysis of Randomized Controlled Trials with the primary intention of detecting the effect of prenatal vitamin D supplementation on the offspring's asthma. Secondary outcomes under respiratory health include eczema, lower respiratory tract infections, Immunoglobulin E positive test, upper respiratory tract infections, and allergic rhinitis.

Methods

A comprehensive search of PubMed, ScienceDirect, Google Scholar, and Cochrane Library databases was performed

SUBMITTER: Tareke AA 

PROVIDER: S-EPMC7691606 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature