Diagnostic value of optic disc retinal nerve fiber layer thickness for diabetic peripheral neuropathy.

ABSTRACT:

Objective

To investigate the value of optic disc retinal nerve fiber layer (RNFL) thickness in the diagnosis of diabetic peripheral neuropathy (DPN).

Methods

Ninety patients with type 2 diabetes, including 60 patients without DPN (NDPN group) and 30 patients with DPN (DPN group), and 30 healthy participants (normal group) were enrolled. Optical coherence tomography (OCT) was used to measure the four quadrants and the overall average RNFL thickness of the optic disc. The receiver operator characteristic curve was drawn and the area under the curve (AUC) was calculated to evaluate the diagnostic value of RNFL thickness in the optic disc area for DPN.

Results

The RNFL thickness of the DPN group was thinner than those of the normal and NDPN groups in the overall average (

SUBMITTER: Wu XH 

PROVIDER: S-EPMC7691684 | biostudies-literature | 2020 Nov.

REPOSITORIES: biostudies-literature