The impact of episodic screening interruption: COVID-19 and population-based cancer screening in Canada.

ABSTRACT:

Background

Population-based cancer screening can reduce cancer burden but was interrupted temporarily due to the COVID-19 pandemic. We estimated the long-term clinical impact of breast and colorectal cancer screening interruptions in Canada using a validated mathematical model.

Methods

We used the OncoSim breast and colorectal cancers microsimulation models to explore scenarios of primary screening stops for 3, 6, and 12 months followed by 6-24-month transition periods of reduced screening volumes. For breast cancer, we estimated changes in cancer incidence over time, additional advanced-stage cases diagnosed, and excess cancer deaths in 2020-2029. For colorectal cancer, we estimated changes in cancer incidence over time, undiagnosed advanced adenomas and colorectal cancers

SUBMITTER: Yong JH 

PROVIDER: S-EPMC7691762 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature