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Predictive Value of Bleb Vascularity after Mitomycin C Augmented Trabeculectomy.


ABSTRACT: To evaluate the relationship between bleb vascularity and surgical outcome one year after mitomycin C (MMC) augmented trabeculectomy. This was a prospective study of 51 eyes of 44 patients after MMC-augmented primary trabeculectomy with follow-up of 12 months. The total vessel area of a bleb was measured with ImageJ software on color photographs of the bleb on day 1 and 14, then months 1, 3, 6 and 12 after trabeculectomy. Blebs were classified clinically as successful (intraocular pressure (IOP) ≤ 18 mmHg and a >30% reduction in IOP without antiglaucoma medications or additional surgical interventions) or failed. Linear regression analysis was performed to determine the correlation of bleb vascularity with IOP and outcome. At 1 year, 40 eyes (78.4%) were classified as successful and 11 eye

SUBMITTER: Wlaz A 

PROVIDER: S-EPMC7692207 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature