The Role of Alcohol Metabolism in the Pathology of Alcohol Hangover.

ABSTRACT: The limited number of available studies that examined the pathology of alcohol hangover focused on biomarkers of alcohol metabolism, oxidative stress and the inflammatory response to alcohol as potentially important determinants of hangover severity. The available literature on alcohol metabolism and oxidative stress is reviewed in this article. The current body of evidence suggests a direct relationship between blood ethanol concentration and hangover severity, whereas this association is not significant for acetaldehyde. The rate of alcohol metabolism seems to be an important determinant of hangover severity. That is, fast elimination of ethanol is associated with experiencing less severe hangovers. An explanation for this observation may be the fact that ethanol-in contrast to acetaldeh

SUBMITTER: Mackus M 

PROVIDER: S-EPMC7692803 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature