The pathophysiological nature of sarcomeres in trigger points in patients with myofascial pain syndrome: A preliminary study.

ABSTRACT:

Background

Myofascial pain syndrome (MPS) has a high global prevalence and is associated with myofascial trigger points (MTrPs) in taut bands or nodules. Little is known about the aetiology. The current study assessed the pathophysiological characteristics of MTrPs in MPS patients.

Methods

Biopsies of the trapezius muscle were collected from the MTrPs of MPS patients (MTrP group; n = 29) and from healthy controls (control group; n = 24), and their morphologies were analysed via haematoxylin-eosin (H&E) and Masson staining. A protein microarray was used to detect the receptor tyrosine kinase (RTK) family proteins. mRNA and long non-coding RNA (lncRNA) sequencing and analysis were conducted, and immunohistochemistry and Western blotting were used to examine the expression of E

SUBMITTER: Jin F 

PROVIDER: S-EPMC7693045 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature