Effect of multiple injections of botulinum toxin into painful masticatory muscles on bone density in the temporomandibular complex.

ABSTRACT:

Background

Adverse effects of masticatory muscle injections of Botulinum Toxin (Btx) have been noted in animal and, less dramatically, human studies.

Objective

Among women treated in multiple community-based private practices, to compare TMJ bone density and mandibular condylar volume between patients with myofascial TMJD receiving multiple masticatory muscle Btx treatments and similarly diagnosed women not receiving such treatment.

Methods

Cohorts consisted of women whose treatment charts indicated a diagnosis of myofascial TMJD: 35 received at least 2 Btx treatment cycles; 44 received none. Bone density at pre-specified regions of interest (ROI) was defined by grey scale values from Cone Beam CT, adjusting for a fixed density phantom included in each scan. Mean bone

SUBMITTER: Raphael KG 

PROVIDER: S-EPMC7693250 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature